Reaction Details
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Report a problem with these dataTarget
Cytochrome P450 2J2
Ligand
BDBM235143
Substrate
n/a
Meas. Tech.
CYP Inhibition Assay
pH
7.4±n/a
Temperature
310.15±n/a K
IC50
6700±n/a nM
Comments
extracted
Citation
Pradhan, NS; Patil, NS; Walavalkar, RR; Kulkarni, NS; Pawar, SB; Pawar, TS Aldehyde derivative of substitute oxazolidinones US Patent US9359341 Publication Date 6/7/2016 More Info.:
Target
Name:
Cytochrome P450 2J2
Synonyms:
CP2J2_HUMAN | CYP2J2
Type:
Enzyme
Mol. Mass.:
57623.04
Organism:
Homo sapiens (Human)
Description:
P51589
Residue:
502
Sequence:
MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITISPVSHRLCAVPQV
Inhibitor
Name:
BDBM235143
Synonyms:
US9359341, Formula B
Type:
Small organic molecule
Emp. Form.:
C20H18ClN3O6S
Mol. Mass.:
463.891
SMILES:
Clc1ccc(s1)C(=O)N(C[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O)C=O |r|
Structure:
