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Target
Disintegrin and metalloproteinase domain-containing protein 9
Ligand
BDBM113588
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
9254±n/a nM
Citation
 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics US Patent  US9365529 Publication Date 6/14/2016 
Target
Name:
Disintegrin and metalloproteinase domain-containing protein 9
Synonyms:
ADAM9 | ADAM9_HUMAN | Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) | KIAA0021 | MCMP | MDC9 | MLTNG
Type:
Enzyme
Mol. Mass.:
90567.68
Organism:
Homo sapiens (Human)
Description:
Q13443
Residue:
819
Sequence:
MGSGARFPSGTLRVRWLLLLGLVGPVLGAARPGFQQTSHLSSYEIITPWRLTRERREAPRPYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYVEGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNKDIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRDCSCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCRFLPGGTLCRGKTSECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCFIEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKCWGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNKNCHCENGWAPPNCETKGYGGSVDSGPTYNEMNTALRDGLLVFFFLIVPLIVCAIFIFIKRDQLWRSYFRKKRSQTYESDGKNQANPSRQPGSVPRHVSPVTPPREVPIYANRFAVPTYAAKQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT
  
Inhibitor
Name:
BDBM113588
Synonyms:
US8633196, 18 | US9365529, 18
Type:
Small organic molecule
Emp. Form.:
C31H34FN5O5S
Mol. Mass.:
607.696
SMILES:
Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(F)cc3)CC2)C(=O)NO)c2ccccc2n1
Structure:
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