Reaction Details Report a problem with these data
Target
Carbonic anhydrase 3
Ligand
BDBM50034172
Substrate
n/a
Meas. Tech.
CA Activity Assay
pH
7.4±n/a
IC50
66730±n/a nM
Comments
extracted
Citation
 Ekinci, D; Kurbanoglu, NI; Salamci, E; Sentürk, M; Supuran, CT Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds. J Enzyme Inhib Med Chem 27:845-8 (2012) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 3
Synonyms:
CA-III | CA3 | CAH3_BOVIN | Carbonate dehydratase III | Carbonic anhydrase 3 | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III
Type:
Enzyme
Mol. Mass.:
29376.92
Organism:
Bos taurus (Cattle)
Description:
Q3SZX4
Residue:
260
Sequence:
MAKEWGYADHNGPDHWHELFPNAKGENQSPIELNTKEISHDPSLKPWTASYDPGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLAAPYRLRQFHLHWGSSDDHGSEHSVDGVKYAAELHLVHWNSKYNSYATALKHADGIAVVGVFLKIGREKGEFQLLLDALDKIKTKGKEAPFNNFNPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPITVSSDQIAKLRTLYSSAENEPPVPLVRNWRPPQPIKGRIVKASFK
  
Inhibitor
Name:
BDBM50034172
Synonyms:
CHEMBL3359227
Type:
Small organic molecule
Emp. Form.:
C23H25N3O
Mol. Mass.:
359.4641
SMILES:
C(COc1cc(nc(n1)-c1ccccc1)-c1ccccc1)CN1CCCC1
Structure:
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