Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM239149
Substrate
n/a
Meas. Tech.
Cannabinoid Receptor Binding Assay
Ki
>1.0e+4±n/a nM
IC50
>1.0e+4±n/a nM
Citation
 Taher, AT; Kadry, HH; Allarà, M; Di Marzo, V; Abadi, AH; Abouzid, KA Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes. J Enzyme Inhib Med Chem 28:436-9 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM239149
Synonyms:
(E)-Ethyl 2-(6-(4-(benzyloxy)phenyl)-4-oxohex-5-enamido)acetate (3k)
Type:
Small organic molecule
Emp. Form.:
C23H25NO5
Mol. Mass.:
395.4483
SMILES:
CCOC(=O)CNC(=O)CCC(=O)\C=C\c1ccc(OCc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: