Reaction Details Report a problem with these data
Target
Alpha-carbonic anhydrase
Ligand
BDBM26996
Substrate
n/a
Meas. Tech.
CA Inhibition Assay
pH
7.5000±n/a
Temperature
298.1500±n/a K
Ki
97000±n/a nM
Comments
extracted
Citation
 Maresca, A; Vullo, D; Scozzafava, A; Supuran, CT Inhibition of the alpha- and beta-carbonic anhydrases from the gastric pathogen Helycobacter pylori with anions. J Enzyme Inhib Med Chem 28:388-91 (2013) [PubMed]  Article 
Target
Name:
Alpha-carbonic anhydrase
Synonyms:
α-Carbonic anhydrase (αCA)
Type:
Enzyme
Mol. Mass.:
28382.59
Organism:
Helicobacter pylori
Description:
J0J440
Residue:
247
Sequence:
MKKTFLIALALAASLIGAENTKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKTDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEDIQKKQNFKEVALDAFLPKTINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR
  
Inhibitor
Name:
BDBM26996
Synonyms:
Phenylboronic acid, 22 | benzeneboronic acid | CHEMBL21485 | phenylboranediol | PhB(OH)2 | phenylboronic acid | Phenyl-boronic acid
Type:
n/a
Emp. Form.:
C6H7BO2
Mol. Mass.:
122.05
SMILES:
B(c1ccccc1)(O)O
Structure:
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