Reaction Details Report a problem with these data
Target
Glutathione peroxidase 1
Ligand
BDBM50390999
Substrate
n/a
Meas. Tech.
Glutathione Peroxidase Activity Assay
pH
7±n/a
Ki
244800±n/a nM
IC50
313400±n/a nM
Comments
extracted
Citation
 Ekinci, D; Cankaya, M; Gül, Ä°; Coban, TA Susceptibility of cord blood antioxidant enzymes glutathione reductase, glutathione peroxidase and glutathione S-transferase to different antibiotics: in vitro approach. J Enzyme Inhib Med Chem 28:824-9 (2013) [PubMed]  Article 
Target
Name:
Glutathione peroxidase 1
Synonyms:
Cellular glutathione peroxidase | GPX1 | GPX1_HUMAN | GPx-1 | GSHPx-1 | Glutathione peroxidase 1 (GPx)
Type:
Enzyme
Mol. Mass.:
21937.89
Organism:
Homo sapiens (Human)
Description:
P07203
Residue:
202
Sequence:
MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA
  
Inhibitor
Name:
BDBM50390999
Synonyms:
CEFOPERAZONE
Type:
Small organic molecule
Emp. Form.:
C25H27N9O8S2
Mol. Mass.:
645.667
SMILES:
CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O |c:26|
Structure:
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