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Target
Asialoglycoprotein receptor 1
Ligand
BDBM408869
Substrate
n/a
Meas. Tech.
SPR Binding Measurements
Kd
12300±n/a nM
Citation
 Liras, S; Mascitti, V; Thuma, B Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of ASGPR US Patent  US10376531 Publication Date 8/13/2019 
Target
Name:
Asialoglycoprotein receptor 1
Synonyms:
ASGP-R 1 | ASGPR 1 | ASGR1 | ASGR1_HUMAN | CLEC4H1 | Hepatic lectin H1
Type:
PROTEIN
Mol. Mass.:
33177.60
Organism:
Homo sapiens (Human)
Description:
ChEMBL_603824
Residue:
291
Sequence:
MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL
  
Inhibitor
Name:
BDBM408869
Synonyms:
US10376531, Compound 31 | US10813942, Compound 31
Type:
Small organic molecule
Emp. Form.:
C13H23NO7
Mol. Mass.:
305.3242
SMILES:
CN([C@H]1[C@H]2OC[C@](CO)(O2)[C@H](O)[C@@H]1O)C(=O)OC(C)(C)C |r|
Structure:
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