Reaction Details Report a problem with these data
Target
Metallo-beta-lactamase type 2
Ligand
BDBM426620
Substrate
n/a
Meas. Tech.
beta-lactamase assay
Ki
100000±n/a nM
Citation
 Chen, Y; Pemberton, OA; Renslo, A; Jaishankar, P Beta-lactamase inhibitors, formulations, and uses thereof US Patent  US10543221 Publication Date 1/28/2020 
Target
Name:
Metallo-beta-lactamase type 2
Synonyms:
B2 metallo-beta-lactamase | BLAN1_KLEPN | Beta-lactamase NDM-1 | Beta-lactamase type II | Metallo-beta-lactamase NDM-1 | Metallo-beta-lactamase type 2 | Metallo-beta-lactamase type II | NDM-1 | New Delhi metallo-beta-lactamase-1 | blaNDM-1
Type:
PROTEIN
Mol. Mass.:
28498.15
Organism:
Klebsiella pneumoniae
Description:
ChEMBL_103887
Residue:
270
Sequence:
MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR
  
Inhibitor
Name:
BDBM426620
Synonyms:
US10543221, Compound 72588 | US10543221, Formula
Type:
Small organic molecule
Emp. Form.:
C12H13O5P
Mol. Mass.:
268.2024
SMILES:
Cc1cc(C)c2c(CP(O)(O)=O)cc(=O)oc2c1
Structure:
Search PDB for entries with ligand similarity: