Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM44795
Substrate
n/a
Meas. Tech.
S1P1 assay
EC50
847±n/a nM
Citation
 Roberts, E; Rosen, H; Brown, S; Guerrero, MA; Peng, X; Poddutoori, R Modulators of sphingosine phosphate receptors US Patent  US10544136 Publication Date 1/28/2020 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM44795
Synonyms:
5-(4-butylphenyl)-3-(4-pyridyl)-1,2,4-oxadiazole | 5-(4-butylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole | MLS000109139 | SMR000105085 | US10544136, Compound 51 | cid_2055443
Type:
Small organic molecule
Emp. Form.:
C17H17N3O
Mol. Mass.:
279.3364
SMILES:
CCCCc1ccc(cc1)-c1nc(no1)-c1ccncc1
Structure:
Search PDB for entries with ligand similarity: