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Target
Acetyl-CoA carboxylase
Ligand
BDBM96481
Substrate
n/a
Meas. Tech.
ACCase Enzymatic Assay
IC50
2015±n/a nM
Citation
 Slomczynska, U; Dimmic, MW; Haakenson, Jr., WP; Bennett, JL; Shortt, BJ; Taylor, CM; Williams, DJ; Slater, M Acetyl-CoA carboxylase modulators US Patent  US10548313 Publication Date 2/4/2020 
Target
Name:
Acetyl-CoA carboxylase
Synonyms:
6.4.1.2 | ACCase | Acetyl-CoA carboxylase
Type:
PROTEIN
Mol. Mass.:
12114.64
Organism:
Zea mays
Description:
ChEMBL_106638
Residue:
109
Sequence:
DSATKTAQALLDFNREGLPLFILANWRGFSGGQRDLFEGILQAGSTIVENLRTYNQPAFVYIPMAGELRGGAWVVVDSKINPDRIECYAERTAKGNVLEPQGLIEIKFR
  
Inhibitor
Name:
BDBM96481
Synonyms:
(3-Cyano-6-thiophen-2-yl-4-trifluoromethyl-pyridin-2-ylsulfanyl)-phenyl-acetic acid | 2-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-2-phenyl-ethanoic acid | 2-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-2-phenylacetic acid | 2-[[3-cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridyl]thio]-2-phenyl-acetic acid | 2-[[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)-2-pyridinyl]thio]-2-phenylacetic acid | MLS001204131 | SMR000523835 | US10548313, Formula Ia-ii | US11375716, Formula Ia-ii | cid_3154832
Type:
Small organic molecule
Emp. Form.:
C19H11F3N2O2S2
Mol. Mass.:
420.428
SMILES:
OC(=O)C(Sc1nc(cc(c1C#N)C(F)(F)F)-c1cccs1)c1ccccc1
Structure:
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