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Target
POU domain, class 2, transcription factor 2
Ligand
BDBM330041
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
2230±n/a nM
Citation
 Bacon, EM; Cai, ZR; Chen, X; Cottell, JJ; Desai, MC; Ji, M; Jin, H; Lazerwith, SE; Mish, MR; Morganelli, PA; Pyun, H; Taylor, JG; Trejo Martin, TA Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections US Patent  US10689399 Publication Date 6/23/2020 
Target
Name:
POU domain, class 2, transcription factor 2
Synonyms:
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 | OCT2 | OCT2 | OTF-2 | OTF2 | Oct-2 | Octamer-binding protein 2 | Octamer-binding transcription factor 2 | Octamer-binding transcription factor 2 (OCT2) | PO2F2_HUMAN | POU domain, class 2, transcription factor 2 | POU2F2
Type:
PROTEIN
Mol. Mass.:
51217.88
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109671
Residue:
479
Sequence:
MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPSTKIKAEDPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP
  
Inhibitor
Name:
BDBM330041
Synonyms:
(4R,12aS)-N-(1-(2,4-difluorophenyl)cyclopropyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide | US10689399, Compound 5 | US11548901, Compound 5 | US9663528, 5
Type:
Small organic molecule
Emp. Form.:
C22H21F2N3O5
Mol. Mass.:
445.416
SMILES:
C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NC4(CC4)c4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12
Structure:
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