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Target
Retinol-binding protein 4
Ligand
BDBM464377
Substrate
n/a
Meas. Tech.
In Vitro Assay
IC50
1.68±n/a nM
Citation
 Petrukhin, K; Cioffi, C; Johnson, G; Dobri, N; Freeman, E; Chen, P; Conlon, M; Zhu, L Octahydropyrrolopyrroles their preparation and use US Patent  US10787453 Publication Date 9/29/2020 
Target
Name:
Retinol-binding protein 4
Synonyms:
PRBP | Plasma retinol-binding protein | RBP | RBP4 | RET4_HUMAN | Retinol-binding protein 4 | Retinol-binding protein 4 (RBP4) | spa binding assay for rbp4
Type:
Protein
Mol. Mass.:
23008.75
Organism:
Homo sapiens (Human)
Description:
P02753
Residue:
201
Sequence:
MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL
  
Inhibitor
Name:
BDBM464377
Synonyms:
US10787453, Compound 65
Type:
Small organic molecule
Emp. Form.:
C21H20F3N5O
Mol. Mass.:
415.4116
SMILES:
Cc1ccc2nnc(C(=O)N3C[C@H]4CN(C[C@H]4C3)c3ccccc3C(F)(F)F)n2c1
Structure:
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