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Target
Galectin-1
Ligand
BDBM468291
Substrate
n/a
Meas. Tech.
Evaluation of Kd Values
Kd
90.0±n/a nM
Citation
 Leffler, H; Nilsson, U; Zetterberg, F Hybrid galactoside inhibitor of galectins US Patent  US10800804 Publication Date 10/13/2020 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM468291
Synonyms:
3,3′-Dideoxy-3′-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-3-(4-methoxy-2,3,5,6-tetrafluoro-benzamido)-1′-sulfanediyl-di-β-D-galactopyranoside | US10800804, Example S16
Type:
Small organic molecule
Emp. Form.:
C30H31F5N4O11S
Mol. Mass.:
750.644
SMILES:
COc1c(F)c(F)c(C(=O)N[C@H]2[C@@H](O)C(CO)O[C@@H](S[C@H]3O[C@H](CO)C(O)C(C3OC(C)=O)n3cc(nn3)-c3cccc(F)c3)C2O)c(F)c1F |r|
Structure:
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