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Target
D(3) dopamine receptor
Ligand
BDBM50392123
Substrate
n/a
Meas. Tech.
radioligand competition assay
Ki
2.19±0.39 nM
Citation
 Dutta, AK Neuroprotective agents for treatment of neurodegenerative diseases US Patent  US10874669 Publication Date 12/29/2020 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50392123
Synonyms:
CHEMBL2152634 | US10874669, Compound (-)-10
Type:
Small organic molecule
Emp. Form.:
C24H34N6S
Mol. Mass.:
438.632
SMILES:
CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)[C@@H]1CCc2nc(N)sc2C1 |r|
Structure:
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