Reaction Details Report a problem with these data
Target
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Ligand
BDBM481595
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
Kd
16±n/a nM
Citation
 Waldmann, H; Martin-Gago, PA; Murarka, S; Klein, C; Bastiaens, P; Wittinghofer, A; Fansa, EK Benzene disulfonamide for the treatment of cancer US Patent  US10913710 Publication Date 2/9/2021 
Target
Name:
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Synonyms:
3',5'-cyclic phosphodiesterase | GMP-PDE delta | PDE6D | PDE6D_HUMAN | PDED | Protein p17 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Type:
PROTEIN
Mol. Mass.:
17418.30
Organism:
Homo sapiens (Human)
Description:
ChEMBL_105761
Residue:
150
Sequence:
MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
  
Inhibitor
Name:
BDBM481595
Synonyms:
US10913710, Compound 11
Type:
Small organic molecule
Emp. Form.:
C29H36ClN5O4S2
Mol. Mass.:
618.21
SMILES:
Clc1ccc(CN(C2CCCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(CC2CCNCC2)Cc2cnccn2)cc1
Structure:
Search PDB for entries with ligand similarity: