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Target
Neuraminidase
Ligand
BDBM482726
Substrate
n/a
Meas. Tech.
Activity assay for influenza virus neuraminidase
IC50
<1±n/a nM
Citation
 Zhang, J; Wang, K; Liu, Y; Li, D Cyclohexene compounds and use thereof US Patent  US10919856 Publication Date 2/16/2021 
Target
Name:
Neuraminidase
Synonyms:
Influenza A Virus Neuraminidase | NA | NRAM_I67A0 | Neuraminidase A
Type:
Enzyme
Mol. Mass.:
52132.25
Organism:
Influenza A virus (A/Tokyo/3/67(H2N2))
Description:
P06820
Residue:
469
Sequence:
MNPNQKIITIGSVSLTIATVCFLMQIAILVTTVTLHFKQHECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPVKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLAGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDRSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKDLRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGRKQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
  
Inhibitor
Name:
BDBM482726
Synonyms:
US10919856, Example 11
Type:
Small organic molecule
Emp. Form.:
C18H31N5O5
Mol. Mass.:
397.4692
SMILES:
COCCO[C@@H]1CCCN(C1)[C@@H]1C=C(C[C@H](NC(N)=N)[C@H]1NC(C)=O)OC=O |r,c:13|
Structure:
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