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Target
Estrogen-related receptor gamma
Ligand
BDBM485062
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
28.0±n/a nM
Citation
 Hwang, SY; Cho, SJ; Kim, J; Chin, J; Hwang, H; Lee, I; Jeon, Y; Lee, J; Jeon, J; Kim, SW Aryl ethene derivative and pharmaceutical composition containing same as active ingredient US Patent  US10934303 Publication Date 3/2/2021 
Target
Name:
Estrogen-related receptor gamma
Synonyms:
ERR gamma-2 | ERR3 | ERR3_HUMAN | ERRG2 | ESRRG | Estrogen receptor-related protein 3 | Estrogen-Related Receptor, gamma | Estrogen-related receptor gamma | KIAA0832 | NR3B3 | Nuclear receptor subfamily 3 group B member 3
Type:
PROTEIN
Mol. Mass.:
51305.00
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1501351
Residue:
458
Sequence:
MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
  
Inhibitor
Name:
BDBM485062
Synonyms:
US10934303, Cmpd No. 20a | US10934303, Example 40 | US11285226, Compound 20a
Type:
Small organic molecule
Emp. Form.:
C27H29BrN2O
Mol. Mass.:
477.436
SMILES:
OCCC\C(=C(/c1ccc(Br)cc1)c1ccc(cc1)N1CCNCC1)c1ccccc1
Structure:
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