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Target
Aurora kinase B
Ligand
BDBM375971
Substrate
n/a
Meas. Tech.
Aurora B Kinase Test
IC50
47950±n/a nM
Citation
 Dahmann, G; Hoffmann, M; Klicic Badoux, J; Lamb, DJ; McCarthy, C; Napier, SC; Parrish, K; Scott, J; Fitzgerald, JL; Walker, E Heteroaryl SYK inhibitors US Patent  US10947243 Publication Date 3/16/2021 
Target
Name:
Aurora kinase B
Synonyms:
Aurora kinase 2 | Aurora kinase B (AURKB) | AIM-1 | Aurora B kinase (aurB) | Aurora B-INCENP | Aurora-related kinase 2 | STK-1 | Serine/threonine-protein kinase aurora B | AURKB_HUMAN | AURKB | AIK2 | AIM1 | AIRK2 | ARK2 | STK1 | STK12 | STK5
Type:
Protein
Mol. Mass.:
39327.72
Organism:
Human
Description:
Q96GD4
Residue:
344
Sequence:
MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
  
Inhibitor
Name:
BDBM375971
Synonyms:
US9914735, Example 50 | US10947243, Example 50
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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