Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM139205
Substrate
n/a
Meas. Tech.
In Vitro Assay
pH
7.4000±n/a
Temperature
277.1500±n/a K
Ki
3±n/a nM
Comments
extracted
Citation
 Montagne, C; Quattropani, A; Sauer, W; Bombrun, A Oxadiazole diaryl compounds US Patent  US8889668 Publication Date 11/18/2014 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 | S1PR1_HUMAN | S1PR1 | CHEDG1 | EDG1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Human
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM139205
Synonyms:
US8889668, I35
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
COc1ccccc1-c1noc(n1)-c1ccc(N2CCCCC2C)c(c1)C(F)(F)F
Structure:
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