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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM50075043
Substrate
n/a
Meas. Tech.
ChEMBL_1468759 (CHEMBL3414298)
IC50
30000±n/a nM
Citation
 Leyva, MJ; Kim, YS; Peach, ML; Schneekloth, JS Synthetic derivatives of the SUMO consensus sequence provide a basis for improved substrate recognition. Bioorg Med Chem Lett 25:2146-51 (2015) [PubMed]  Article 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9_HUMAN | UBE2I | UBC9 | UBCE9 | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Human
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM50075043
Synonyms:
CHEMBL3410376
Type:
Small organic molecule
Emp. Form.:
C25H46N6O7
Mol. Mass.:
542.34
SMILES:
CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(N)=O |r|
Structure:
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