Reaction Details Report a problem with these data
Target
Neuraminidase
Ligand
BDBM50489419
Substrate
n/a
Meas. Tech.
ChEMBL_935175 (CHEMBL2317337)
IC50
5760±n/a nM
Citation
 Feng, E; Shin, WJ; Zhu, X; Li, J; Ye, D; Wang, J; Zheng, M; Zuo, JP; No, KT; Liu, X; Zhu, W; Tang, W; Seong, BL; Jiang, H; Liu, H Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors. J Med Chem 56:671-84 (2013) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NRAM_I33A0 | NA
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50489419
Synonyms:
CHEMBL2315317
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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