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Target
Glycerol-3-phosphate acyltransferase 1, mitochondrial
Ligand
BDBM50498264
Substrate
n/a
Meas. Tech.
ChEMBL_1498249 (CHEMBL3583672)
IC50
47300±n/a nM
Citation
 Outlaw, VK; Wydysh, EA; Vadlamudi, A; Medghalchi, SM; Townsend, CA Design, Synthesis, and Evaluation of 4- and 5-Substituted  Medchemcomm 5:826-830 (2014) [PubMed]  Article 
Target
Name:
Glycerol-3-phosphate acyltransferase 1, mitochondrial
Synonyms:
2.3.1.15 | GPAT-1 | Glycerol-3-phosphate acyltransferase 1, mitochondrial | P90 | GPAT1_MOUSE | Gpam | Gpat1
Type:
PROTEIN
Mol. Mass.:
93718.58
Organism:
Mouse
Description:
ChEMBL_109810
Residue:
827
Sequence:
MEESSVTVGTIDVSYLPSSSEYSLGRCKHTSEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLSSSRVQEAIAEVAAELNPDGSAQQQSKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDETPDGRKDILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLEGQSQKPVSAPLSLEQALLPAILPSRPNDVADEHQDLSSNESRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSIYAVLNKRCSGGSAGGLGNLISQEQLVRKAASLCYLLSNEGTISLPCQTFYQVCHETVGKFIQYGILTVAEQDDQEDVSPGLAEQQWDKKLPELNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPESEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRVSVLELSSTFLPQCNRQKLLEYILSFVVL
  
Inhibitor
Name:
BDBM50498264
Synonyms:
CHEMBL3580994
Type:
Small organic molecule
Emp. Form.:
C21H27NO5S
Mol. Mass.:
405.52
SMILES:
CCCCCCCCS(=O)(=O)Nc1ccc(cc1C(O)=O)-c1ccc(O)cc1
Structure:
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