Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 2
Ligand
BDBM50634284
Substrate
n/a
Meas. Tech.
ChEMBL_2380358
EC50
22±n/a nM
Citation
 Stiller, T; Merk, D Exploring Fatty Acid Mimetics as NR4A Ligands. J Med Chem 66:15362-15369 (2023) [PubMed] 
Target
Name:
Nuclear receptor subfamily 4 group A member 2
Synonyms:
NR4A2_HUMAN | NR4A2 | NOT | NURR1 | TINUR
Type:
PROTEIN
Mol. Mass.:
66603.77
Organism:
Human
Description:
ChEMBL_453027
Residue:
598
Sequence:
MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
  
Inhibitor
Name:
BDBM50634284
Synonyms:
CHEMBL5427562
Type:
Small organic molecule
Emp. Form.:
C14H10Cl2O3
Mol. Mass.:
297.14
SMILES:
OC(=O)c1cccc(OCc2ccc(Cl)cc2Cl)c1
Structure:
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