| Assay Method Information | |
| | Receptor Binding Assay |
| Description: | Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of the three compounds was calculated from IC50, Kd values of labelled MIT for PKR1 and PKR2 being 4 pM and 1.24 pM (PerkinElmer, Membrane Target Systems). |
| Affinity data for this assay | |
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