| Assay Method Information | |
| | SAR Analysis for the identification of selective inhibits of the transient receptor potential cation channel C4 (TRPC4): Automated Electrophysiology |
| Description: | Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center Affiliation: Johns Hopkins University, School of Medicine Screening Center PI: Min Li, Ph.D. Assay Provider: Michael Zhu, Ph.D., Ohio State University Network: Molecular Libraries Probe Production Centers Network (MLPCN) Grant Proposal Number: 1 R21 NS056942-01 Grant Proposal PI: Michael Zhu, Ph.D., Ohio State University Assay Implementation: Jie Shi, Melissa Miller, Shunyou Long M.S., David Meyers Ph.D., Meng Wu Ph.D., Owen McManus Ph.D. Name: SAR Analysis for the identification of selective inhibitors of the transient receptor potential cation channel C4 (TRPC4): Automated Electrophysiology Description: The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiologcal assays using a QPatch16 automated electrophysiology instrument. Whole cell recordings were |
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