| Assay Method Information | |
| | ChEMBL_2251918 (CHEMBL5166128) |
| Description: | Inhibition of C-terminal Avi and 6His-tagged human KRAS 2B G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of SOS mediated nucleotide exchange preincubated for 4 hrs followed by SOS1 addition by HTRF assay |
| Affinity data for this assay | |
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