| Assay Method Information | |
| | ChEMBL_1513806 (CHEMBL3611124) |
| Description: | Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-H(p)ETE preincubated for 15 mins followed by substrate and ionophore addition measured after 10 mins by HPLC analysis |
| Affinity data for this assay | |
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