Assay Method Information

Assay Name:  Guanidine Influx Assay
Description:  A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay uses 14C-guanidine hydrochloride in combination with various known voltage-gated sodium channel modulators that produce maintained influx, to assay the potency of test agents.
Affinity data for this assay
 

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