| Assay Method Information | |
| | Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01 |
| Description: | University of New Mexico Assay Overview: Assay Support: NIH 1 R03 MH093193-01A1 High Throughput Screening for inhibitors of the ABC transporter ABCB6 PI: Partha Krishnamurthy, Ph.D. Screening Center PI: Larry Sklar, Ph.D. / UNMCMD Screening Lead: Mohiuddin Khan, Ph.D. Assay Implementation: Stephanie Chavez, Dominique Perez, Matthew Garcia, J. Jacob Strouse, Ph.D., Mark Carter, M.S., Anna Waller, Ph.D. UNM Cheminformatics: Cristian Bologa, Ph.D., Oleg Ursu, Ph.D. Chemistry: University of Kansas Specialized Chemistry Center KU Specialized Chemistry Center PI: Jeff Aube, Ph.D. KU SCC Project Manager: Jennifer E. Golden. Ph.D. Assay Background and Significance: The goal of this project is to implement a high throughput screening (HTS) assay to identify and develop selective chemical probes that regulate ABCB6 expression or function. The long-term objective is to use these novel pharmacological tools to understand not only the significance of ABCB6 in tumor growth and proliferation a |
| Affinity data for this assay | |
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