| Assay Method Information | |
| | Radioligand Binding Assays |
| Description: | IC50 Values for Example 1 and the Reference Compound 3-(3,4-Dichlorophenoxy)Azetidine Hydrochloric Acid Salt Employing Radioligand Binding Assays Using Cells Expressing Human Transporters and ReceptorsIn another binding study employing the same assays for the three monoamine transporters as described herein above, one of the compounds of the invention (Example 1A) was tested at different concentrations in order to obtain dose-response curves. Furthermore, the above mentioned Reference Compound was tested in the same assays at different concentrations and the IC50 values of both of the compounds are presented in Table 6. |
| Affinity data for this assay | |
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