| Assay Method Information | |
| | ChEMBL_1505545 (CHEMBL3595696) |
| Description: | Inhibition of ADAM17 in human A549 cells assessed as potentiation of gefitinib-mediated inhibition of cell viability by measuring gefitinib IC50 at 40 uM incubated for 1 hr followed by gefitinib addition measured after 72 hrs by CellTiter-Glo assay (Rvb = 8.4 microM) |
| Affinity data for this assay | |
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