Assay Method Information

Assay Name:  ChEMBL_2452034
Description:  Covalent inhibition of NLRP3 in mouse BMDMs assessed as reduction in LPS/nigericin induced IL-1beta secretion pretreated with LPS for 3 hrs followed by compound addition for 30 mins prior to nigericin addition and measured after 30 mins by ELISA
Affinity data for this assay
 

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