Assay Method Information | |
| ChEMBL_1995597 (CHEMBL4629492) |
Description: | Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on topotecan-induced cytotoxicity by measuring topotecan IC50 at 3 uM after 72 hrs by CCK8 assay (Rvb = 201.31 +/- 25.89 nM) |
Affinity data for this assay | |
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