| Assay Method Information | |
| | ChEMBL_2330611 |
| Description: | Negative allosteric modulator activity at human P-gp G1114I mutant expressed in HEK293FT cells assessed as reversal of P-gp mediated PTX resistance by measuring paclitaxel IC50 incubated for 5 days by MTS assay (Rvb = 10.2 +/- 2.4 nM) |
| Affinity data for this assay | |
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