| Assay Method Information | |
| | GGTase-1 Scintillation Proximity Assay |
| Description: | Compounds were tested as inhibitors of GGTase-1 in vitro using purified human enzyme to catalyze the reaction between [3H] GGPP and a biotinylated peptide substrate. Reaction was terminated by addition of streptavidin scintillation proximity assay beads (Amersham), and the mixtures were subsequently analyzed by scintillation counting |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |