| Assay Method Information | |
| | GGTase-I Activity Assay |
| Description: | The in vitro activity of compounds inhibiting GGTase-1 was determined by measuring the transfer of [3H]-geranylgeranylpyrophosphate to substrate Ha-Ras-CVLL. The incorporated radioactivity was quantified by scintillation counting. |
| Affinity data for this assay | |
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