| Assay Method Information | |
| | ChEMBL_1673977 (CHEMBL4024006) |
| Description: | Inhibition of RIPK1 in human HT-29 cells assessed as decrease in TNFalpha/AT-406/zVAD-FMK-induced MLKL phosphorylation at S358 residue preincubated for 30 mins followed by TNFalpha/AT-406/zVAD-FMK addition measured after 6 hrs by WES assay |
| Affinity data for this assay | |
|---|---|
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