| Assay Method Information | |
| | ChEMBL_1809635 (CHEMBL4309095) |
| Description: | Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced channel current by measuring acetylcholine EC50 at 10 uM at -90 mV holding potential preincubated for 2 mins followed by co-application with acetylcholine for 10 secs by two-electrode voltage clamp method (Rvb = 256.4 +/- 20.1 uM) |
| Affinity data for this assay | |
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