Assay Method Information

Assay Name:  ChEMBL_1928982 (CHEMBL4432158)
Description:  Inhibition of GARFTase in human KB cells expressing RFC/FR-alpha/PCFT assessed as decrease in incorporation of [14C(U)]-glycine into [14C]formyl GAR incubated for 1 hr followed by addition of [14C(U)]-glycine measured after 16 hrs in presence of azaserine
Affinity data for this assay
 

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