| Assay Method Information | |
| | Human 5-HT2A Binding Assay |
| Description: | The experiment was carried out at Cerep Contract Laboratories (Cat. ref. #471).Compound (I) was also tested in an in vivo set up demonstrating central effects of the compound. By in vivo binding, the compound's in vivo affinity for D2 receptors was assessed and occupancy of 60% of the target was observed. Occupancy of D2 receptors is closely linked to antipsychotic effects in animal models and in patients. |
| Affinity data for this assay | |
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