| Assay Method Information | |
| | ChEMBL_1666073 (CHEMBL4015869) |
| Description: | Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in ATP-induced Ca2+ activation-mediated chloride current by measuring decrease in iodide influx preincubated for 10 mins followed by ATP/iodide addition by fluorescence assay |
| Affinity data for this assay | |
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