| Assay Method Information | |
| | ChEMBL_2548833 |
| Description: | Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed as reduction in KRAS G12C mutant activation preincubated for 10 mins with KRAS followed by SOS2 addition measured after 30 mins in presence of EDA-GTP-DY-647P1 by HTRF analysis |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |