Assay Method Information

Assay Name:  ChEMBL_1364860 (CHEMBL3294823)
Description:  Antagonist activity at human PXR transfected in human HepG2 cells co-transfected with pSG5-RXR/pCMV-beta-galactosidase/p(CYP3A4)-TK-Luc assessed as inhibition of rifaximin-induced transactivation after 18 hrs by luciferase reporter gene assay
Affinity data for this assay
 

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