Assay Method Information | |
| ChEMBL_1855746 (CHEMBL4356475) |
Description: | Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 7 uM after 48 hrs by MTT assay (Rvb = 2120 nM) |
Affinity data for this assay | |
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