Assay Method Information

Assay Name:  ChEMBL_1855746 (CHEMBL4356475)
Description:  Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 7 uM after 48 hrs by MTT assay (Rvb = 2120 nM)
Affinity data for this assay
 

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