| Assay Method Information | |
| | ChEMBL_2199026 (CHEMBL5111542) |
| Description: | Inhibition of DNA polymerase theta in LIG4 knock out HEK293T cells assessed as decrease in MMEJ-mediated DNA repair preincubated for 1 day followed by lentivirus solution addition for 24 hrs prior to media replacement with compound and measured after 96 hrs by flow cytometry based traffic-light reporter assay |
| Affinity data for this assay | |
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