| Assay Method Information | |
| | ChEMBL_2484872 |
| Description: | Inhibition of N-terminal Strep tagged/TEC fused human IDH1 R132H mutant extracted from Escherichia coli BL21 (DE3) cells using alpha-ketoglutarate as substrate assessed as reduction in 2-HG levels preincubated for 30 mins in presence of NADPH followed by substrate addition by LC-MS/MS analysis |
| Affinity data for this assay | |
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