Affinity DataKi: 0.0640nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
Affinity DataKi: 0.0690nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
Ligand Info
Ligand Info
Ligand Info
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Ligand Info
Affinity DataKd: 0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand Info
Ligand Info
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Ligand Info
Ligand Info
Ligand Info
Affinity DataKd: 0.540nMAssay Description:Binding affinity to human N-terminal ATPase domain of Hsp90 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 0.540nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 0.546nMAssay Description:Binding affinity to human HSP90AB1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand Info
Ligand Info
Ligand Info
Affinity DataKd: 0.710nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Ligand Info
Ligand Info
Ligand Info
Ligand Info
Ligand Info
Ligand Info
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Ligand Info
Affinity DataIC50: 1nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
Ligand Info
Ligand Info
Affinity DataKi: 1.10nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
Ligand Info
Ligand Info
Ligand Info
Ligand Info
Ligand Info
Ligand Info
Ligand Info



3D Structure (crystal)












































