Compile Data Set for Download or QSAR
Report error Found 40 of affinity data for UniProtKB/TrEMBL: E9Q401
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652470(CHEMBL5639852)
Affinity DataEC50:  13nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652453(CHEMBL5646836)
Affinity DataEC50:  22nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652463(CHEMBL5641800)
Affinity DataEC50:  23nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652462(CHEMBL5639167)
Affinity DataEC50:  26nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652464(CHEMBL5646884)
Affinity DataEC50:  28nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652465(CHEMBL5639480)
Affinity DataEC50:  34nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652466(CHEMBL5639313)
Affinity DataEC50:  48nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652459(CHEMBL5641840)
Affinity DataEC50:  50nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652469(CHEMBL5639295)
Affinity DataEC50:  59nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652451(CHEMBL5639861)
Affinity DataEC50:  96nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652456(CHEMBL5647032)
Affinity DataEC50:  136nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652448(CHEMBL5646849)
Affinity DataEC50:  180nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652452(CHEMBL5647159)
Affinity DataEC50:  220nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652458(CHEMBL5639293)
Affinity DataEC50:  234nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652450(CHEMBL5641758)
Affinity DataEC50:  460nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652436(CHEMBL5641625)
Affinity DataEC50:  696nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652457(CHEMBL5647467)
Affinity DataEC50:  859nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50294528(methyl orsellinate | methyl 2,4-dihydroxy-6-methyl...)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652468(CHEMBL5647581)
Affinity DataEC50:  1.14E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652449(CHEMBL5639305)
Affinity DataEC50:  1.23E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50421670(CHEMBL5188974)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of RyR2 in Casq2 gene knockout mouse cardiomyocytes assessed as reduction in calcium sparks frequency incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652447(CHEMBL5641646)
Affinity DataEC50:  2.92E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50421669(CHEMBL5180539)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of RyR2 in Casq2 gene knockout mouse cardiomyocytes assessed as reduction in calcium sparks frequency incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652437(CHEMBL5639574)
Affinity DataEC50:  4.08E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataEC50:  9.90E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652455(CHEMBL5641717)
Affinity DataEC50:  2.50E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652438(CHEMBL5647410)
Affinity DataEC50:  2.94E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652461(CHEMBL5647453)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652460(CHEMBL5646489)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652467(CHEMBL5647208)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652435(CHEMBL5639308)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652439(CHEMBL5647160)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652443(CHEMBL5639709)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652442(CHEMBL5647325)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652441(CHEMBL5646903)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652440(CHEMBL5646642)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652446(CHEMBL5639268)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652445(CHEMBL5646503)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652444(CHEMBL5639384)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652454(CHEMBL5639438)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed