Compile Data Set for Download or QSAR
Report error Found 154 of affinity data for UniProtKB/TrEMBL: O07442
TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397464BDBM397464(US9988375, Compound 43 | US10676470, Compound 43 |...)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453275BDBM453275(US10730826, Compound 1a-non-racemic | US10730826, ...)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453275BDBM453275(US10730826, Compound 1a-non-racemic | US10730826, ...)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453289BDBM453289(US10730826, Compound 2a | US11325884, Compound 2a)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397464BDBM397464(US9988375, Compound 43 | US10676470, Compound 43 |...)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453289BDBM453289(US10730826, Compound 2a | US11325884, Compound 2a)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453275BDBM453275(US10730826, Compound 1a-non-racemic | US10730826, ...)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397464BDBM397464(US9988375, Compound 43 | US10676470, Compound 43 |...)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453323BDBM453323(US10730826, Compound 74 | BDBM553828)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453289BDBM453289(US10730826, Compound 2a | US11325884, Compound 2a)
Affinity DataIC50: 0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453352BDBM453352(US10730826, Compound 42a | BDBM553856)
Affinity DataIC50: 0.0600nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453329BDBM453329(BDBM553832 | US10730826, Compound 47a)
Affinity DataIC50: 0.0600nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453359BDBM453359(BDBM553862 | US10730826, Compound 52a)
Affinity DataIC50: 0.0600nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453333BDBM453333(BDBM553836 | US10730826, Compound 48a)
Affinity DataIC50: 0.0700nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453293BDBM453293(US10730826, Compound 4a | US11325884, Compound 4a)
Affinity DataIC50: 0.0700nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453312BDBM453312(BDBM553818 | BDBM453343 | US10730826, Compound 12a)
Affinity DataIC50: 0.0800nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453312BDBM453312(BDBM553818 | BDBM453343 | US10730826, Compound 12a)
Affinity DataIC50: 0.0800nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453342BDBM453342(US10730826, Compound 32a | BDBM553845)
Affinity DataIC50: 0.0800nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453309BDBM453309(US10730826, Compound 9a | US10730826, Compound 10a...)
Affinity DataIC50: 0.0800nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453335BDBM453335(BDBM553838 | US10730826, Compound 57a)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453369BDBM453369(BDBM553871 | US10730826, Compound 63a)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453336BDBM453336(BDBM553839 | US10730826, Compound 26a)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453328BDBM453328(US10730826, Compound 21 | BDBM553831)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453330BDBM453330(US10730826, Compound 50a | BDBM553833)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453353BDBM453353(BDBM553857 | US10730826, Compound 43a)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453345BDBM453345(BDBM553848 | US10730826, Compound 35a)
Affinity DataIC50: 0.100nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453362BDBM453362(US10730826, Compound 56a | BDBM553865)
Affinity DataIC50: 0.100nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453331BDBM453331(US10730826, Compound 55a | BDBM553834)
Affinity DataIC50: 0.120nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453309BDBM453309(US10730826, Compound 9a | US10730826, Compound 10a...)
Affinity DataIC50: 0.120nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453344BDBM453344(BDBM553847 | US10730826, Compound 34a)
Affinity DataIC50: 0.130nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453368BDBM453368(US10730826, Compound 62a | BDBM553870)
Affinity DataIC50: 0.140nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453305BDBM453305(US10730826, Compound 5a | US11325884, Compound 5a)
Affinity DataIC50: 0.150nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453341BDBM453341(US10730826, Compound 31a | BDBM553844)
Affinity DataIC50: 0.150nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453371BDBM453371(BDBM553873 | US10730826, Compound 65a)
Affinity DataIC50: 0.160nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453306BDBM453306(US10730826, Compound 6a | US11325884, Compound 6a)
Affinity DataIC50: 0.190nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453332BDBM453332(BDBM553835 | US10730826, Compound 69a)
Affinity DataIC50: 0.210nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453340BDBM453340(US10730826, Compound 30a | BDBM553843)
Affinity DataIC50: 0.210nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453334BDBM453334(BDBM553837 | US10730826, Compound 49a)
Affinity DataIC50: 0.230nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453337BDBM453337(BDBM553840 | US10730826, Compound 27a)
Affinity DataIC50: 0.270nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453339BDBM453339(US10730826, Compound 29a | BDBM553842)
Affinity DataIC50: 0.310nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453308BDBM453308(US10730826, Compound 8a | US11325884, Compound 8a)
Affinity DataIC50: 0.340nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453338BDBM453338(US10730826, Compound 28a | BDBM553841)
Affinity DataIC50: 0.340nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453370BDBM453370(BDBM553872 | US10730826, Compound 64a)
Affinity DataIC50: 0.400nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453357BDBM453357(BDBM553861 | US10730826, Compound 51a)
Affinity DataIC50: 0.400nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453367BDBM453367(US10730826, Compound 61a | BDBM553869)
Affinity DataIC50: 0.430nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453357BDBM453357(BDBM553861 | US10730826, Compound 51a)
Affinity DataIC50: 0.440nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453318BDBM453318(US10730826, Compound 18a | BDBM553824)
Affinity DataIC50: 0.5nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453318BDBM453318(US10730826, Compound 18a | BDBM553824)
Affinity DataIC50: 0.5nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 453290BDBM453290(US10730826, Compound 3a | US11325884, Compound 3a)
Affinity DataIC50: 0.640nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397464BDBM397464(US9988375, Compound 43 | US10676470, Compound 43 |...)
Affinity DataIC50: 1nMAssay Description:The specific assay conditions were as follows. Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

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