Compile Data Set for Download or QSAR
Report error Found 121 of affinity data for UniProtKB/TrEMBL: O14779
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265555BDBM50265555((2S)-N-Phenyl-2-{[4-({[5-(phenylsulfonyl)-2-(trifl...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265554BDBM50265554((2S)-N-(tert-Butyl)-2-{[4-({[5-(phenylsulfonyl)-2-...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265547BDBM50265547(N-{1-[1-(3,3-Dimethylbutanoyl)-L-prolyl]piperidin-...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308711BDBM50308711(4-{[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phe...)
Affinity DataIC50: 20nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308710BDBM50308710(3-{[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phe...)
Affinity DataIC50: 20nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265499BDBM50265499(N-[1-(1H-Imidazol-1-ylacetyl)piperidin-4-yl]-5-(ph...)
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265553BDBM50265553((2S)-N-Ethyl-2-{[4-({[5-(phenylsulfonyl)-2-(triflu...)
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265580BDBM50265580((2S)-N,N-Dimethyl-2-{[4-({[5-(phenylsulfonyl)-2-(t...)
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265583BDBM50265583(N-{1-[1-(3,3-Dimethylbutyl)-L-prolyl]piperidin-4-y...)
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308712BDBM50308712(5-(Phenylsulfonyl)-N-(1-{[3-(2H-tetrazol-5-yl)phen...)
Affinity DataIC50: 30nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308701BDBM50308701(5-(Phenylsulfonyl)-N-{1-[(3S)-pyrrolidin-3-ylcarbo...)
Affinity DataIC50: 40nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265581BDBM50265581(N-{1-[1-(Morpholin-4-ylcarbonyl)-L-prolyl]piperidi...)
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308692BDBM50308692(N-(1-{[6-(Dimethylamino)pyridin-3-yl]carbonyl}pipe...)
Affinity DataIC50: 40nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265545BDBM50265545(N-[1-(1-Isobutyryl-L-prolyl)piperidin-4-yl]-5-(phe...)
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265584BDBM50265584(N-{1-[1-(Cyclohexylmethyl)-L-prolyl]piperidin-4-yl...)
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265546BDBM50265546(N-{1-[1-(2,2-Dimethylpropanoyl)-L-prolyl]piperidin...)
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308691BDBM50308691(5-(Phenylsulfonyl)-2-(trifluoromethyl)-N-(1-{[6-(t...)
Affinity DataIC50: 50nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265549BDBM50265549(N-{1-[1-(Cyclohexylcarbonyl)-L-prolyl]piperidin-4-...)
Affinity DataIC50: 50nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308698BDBM50308698(tert-Butyl(3R)-3-{[4-({[5-(phenylsulfonyl)-2-(trif...)
Affinity DataIC50: 50nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308688BDBM50308688(5-(Phenylsulfonyl)-N-[1-(pyridin-3-ylcarbonyl)pipe...)
Affinity DataIC50: 60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265500BDBM50265500(tert-Butyl (2S)-2-{[4-({[5-(Phenylsulfonyl)-2-(tri...)
Affinity DataIC50: 60nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308703BDBM50308703(2-[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phen...)
Affinity DataIC50: 60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308702BDBM50308702(5-(Phenylsulfonyl)-N-{1-[(3R)-pyrrolidin-3-ylcarbo...)
Affinity DataIC50: 60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265500BDBM50265500(tert-Butyl (2S)-2-{[4-({[5-(Phenylsulfonyl)-2-(tri...)
Affinity DataIC50: 60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265500BDBM50265500(tert-Butyl (2S)-2-{[4-({[5-(Phenylsulfonyl)-2-(tri...)
Affinity DataEC50:  60nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265552BDBM50265552(N-[1-(1-Isonicotinoyl-L-prolyl)piperidin-4-yl]-5-(...)
Affinity DataIC50: 70nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308692BDBM50308692(N-(1-{[6-(Dimethylamino)pyridin-3-yl]carbonyl}pipe...)
Affinity DataEC50:  70nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308681BDBM50308681(N-(1-Benzoylpiperidin-4-yl)-5-(phenylsulfonyl)-2-t...)
Affinity DataIC50: 70nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308697BDBM50308697(tert-Butyl(3S)-3-{[4-({[5-(phenylsulfonyl)-2-(trif...)
Affinity DataIC50: 70nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265550BDBM50265550(N-[1-(1-Benzoyl-L-prolyl)piperidin-4-yl]-5-(phenyl...)
Affinity DataIC50: 70nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308689BDBM50308689(N-(1-Isonicotinoylpiperidin-4-yl)-5-(phenylsulfony...)
Affinity DataIC50: 80nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308698BDBM50308698(tert-Butyl(3R)-3-{[4-({[5-(phenylsulfonyl)-2-(trif...)
Affinity DataEC50:  80nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308713BDBM50308713(N-{1-[(3-Cyanophenyl)sulfonyl]piperidin-4-yl}-5-(p...)
Affinity DataIC50: 90nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265505BDBM50265505(N-[1-(5-oxo-L-Prolyl)piperidin-4-yl]-5-(phenylsulf...)
Affinity DataIC50: 90nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265548BDBM50265548(N-[1-(N,N-Dimethylglycyl-L-prolyl)piperidin-4-yl]-...)
Affinity DataIC50: 90nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308714BDBM50308714(3-[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phen...)
Affinity DataIC50: 100nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308700BDBM50308700(5-(Phenylsulfonyl)-N-[1-(piperidin-4-ylacetyl)pipe...)
Affinity DataIC50: 100nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265480BDBM50265480(N-[1-(Morpholin-4-ylacetyl)piperidin-4-yl]-5-(phen...)
Affinity DataIC50: 100nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308711BDBM50308711(4-{[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phe...)
Affinity DataEC50:  110nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265503BDBM50265503(5-(Phenylsulfonyl)-N-(1-L-prolylpiperidin-4-yl)-2-...)
Affinity DataIC50: 110nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265503BDBM50265503(5-(Phenylsulfonyl)-N-(1-L-prolylpiperidin-4-yl)-2-...)
Affinity DataIC50: 110nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308690BDBM50308690(N-{1-[(6-Chloropyridin-3-yl)carbonyl]piperidin-4-y...)
Affinity DataIC50: 110nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265551BDBM50265551(N-(1-{1-[4-(Dimethylamino)benzoyl]-L-prolyl}piperi...)
Affinity DataIC50: 110nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265479BDBM50265479(5-(Phenylsulfonyl)-N-[1-(pyrrolidin-1-ylacetyl)pip...)
Affinity DataIC50: 110nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308715BDBM50308715(4-[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phen...)
Affinity DataIC50: 120nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265501BDBM50265501(tert-Butyl (2R)-2-{[4-({[5-(Phenylsulfonyl)-2-(tri...)
Affinity DataIC50: 120nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308689BDBM50308689(N-(1-Isonicotinoylpiperidin-4-yl)-5-(phenylsulfony...)
Affinity DataEC50:  120nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265582BDBM50265582(N-[1-(1-Methyl-L-prolyl)piperidin-4-yl]-5-(phenyls...)
Affinity DataIC50: 120nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308699BDBM50308699(5-(Phenylsulfonyl)-N-[1-(piperidin-4-ylcarbonyl)pi...)
Affinity DataIC50: 120nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSecreted frizzled-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265501BDBM50265501(tert-Butyl (2R)-2-{[4-({[5-(Phenylsulfonyl)-2-(tri...)
Affinity DataIC50: 120nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
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